DNA Structure and Replication – Section 1

16. What is the only common methylation in the DNA of eukaryotes?

A. Adenosine in GpA dinucleotides
B. Guanosine in ApGpA trinucleotides
C. Cytosine in CpG dinucleotides
D. None of the above

Correct Answer: C. Cytosine in CpG dinucleotides

17. DNAs when charged, migrate in a gel towards the

A. positive pole
B. negative pole
C. will not migrate
D. none of these

Correct Answer: A. positive pole

18. What is the approximate size (in kb) of the E. coli genome?

A. 3000 kilobase
B. 4500 kilobase
C. 5500 kilobase
D. 6500 kilobase

Correct Answer: B. 4500 kilobase

19. In the study of one experiment it was found that the value of Tm for DNA is = 40° C. If the cell has 20% GC at the above Tm, then what will be value of ‘Tm’ if the GC% increases to 60%?

A. Remains same
B. Increases
C. Decreases
D. Can not be compared

Correct Answer: B. Increases

20. What is the range of melting point temperatures (Tm) for most DNA molecules?

A. 50 to 60°C
B. 60 to 80°C
C. 70 to 90°C
D. 80 to l00°C

Correct Answer: D. 80 to l00°C

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