Antimicrobial Chemotherapeutic Agents – Section 1

41. The antibiotics not having good activity against Enterobacteriaceae is

A. clindamycin
B. cefoxitin
C. trimethoprim-sulphamethoxazole
D. ciprofloxacin

Correct Answer: A. clindamycin

42. Quinones and related antibiotics are

A. tetracyclines
B. actinorhodin
C. mitomycin
D. all of these

Correct Answer: D. all of these

43. Both penicillin and fluoroquinolones

A. bind to and inactivate a bacterial protein
B. inhibit the cross-linking of peptidoglycan
C. are inactivated by β-lactamase
D. must be transported into the cytoplasm in order to act

Correct Answer: A. bind to and inactivate a bacterial protein

44. A broad-spectrum antibiotic such as chloramphenicol is one that

A. kills both Gram positive and Gram negative bacteria
B. kills all bacteria
C. kills numerous types of microbes
D. kills all microorganisms

Correct Answer: C. kills numerous types of microbes

45. Vancomycin inhibits peptidoglycan synthesis by binding

A. D-alanyl – D-alanine
B. alanine racemase
C. D-alanyl – D-alanine synthetase
D. amidase

Correct Answer: A. D-alanyl – D-alanine

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