Antimicrobial Chemotherapeutic Agents – Section 1

36. The scientist who first discovered the substance penicillin was

A. Joseph Lister
B. Alexander Fleming
C. Paul Ehrlich
D. none of these

Correct Answer: B. Alexander Fleming

37. The larger the __________ , the better the chemotherapeutic agent.

A. therapeutic index
B. therapeutic dose
C. selective toxicity
D. spectrum

Correct Answer: A. therapeutic index

38. Chelate forming peptide antibiotic are/is

A. bleomycins
B. sideromycins
C. both (a) and (b)
D. vancomycin

Correct Answer: C. both (a) and (b)

39. With which of the following aminoglycosides interfere?

A. Protein synthesis
B. DNA function
C. Cell wall synthesis
D. Cell membrane function

Correct Answer: A. Protein synthesis

40. Which of the following protein synthesis mechanisms may be affected by particular drugs?

A. Peptide bond formation
B. mRNA translocation
C. Aminoacyl-tRNA binding
D. All of these

Correct Answer: D. All of these

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