Antimicrobial Chemotherapeutic Agents – Section 1

11. Which of the following drugs involves modification of the drug by enzymatic modification or degradation of its active element to alter its/their resistance?

A. Penicillins
B. Chloramphenicol
C. Aminoglycosides
D. All of these

Correct Answer: D. All of these

12. Who developed the concept of specific toxicity?

A. Pasteur
B. Fleming
C. Watson
D. Ehrlich

Correct Answer: D. Ehrlich

13. When using alcohol as an antiseptic, which concentration is considered most effective?

A. 95%
B. 50%
C. 70%
D. 25%

Correct Answer: C. 70%

14. Fluoroquinolones are antibiotics which inhibit

A. DNA polymerase
B. RNA polymerase
C. DNA gyrase
D. Cross-linking of peptidoglycan

Correct Answer: C. DNA gyrase

15. Which of the following is used only in life-threatening situations when no other drug is adequate?

A. Penicillin
B. Tetracycline
C. Chloramphenicol
D. Streptomycin

Correct Answer: C. Chloramphenicol

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